Low Intensity Focused Ultrasound for Epilepsy- A New Approach to Neuromodulation.

ABSTRACT: Patients with drug-resistant epilepsy (DRE) who are not surgical candidates have unacceptably few treatment options. Benefits of implanted electrostimulatory devices are still largely palliative, and many patients are not eligible to receive them. A new form of neuromodulation, low intensity focused ultrasound (LIFUS), is rapidly emerging, and has many potential intracranial applications. LIFUS can noninvasively target tissue with a spatial distribution of highly focused acoustic energy that ensures a therapeutic effect only at the geometric focus of the transducer. A growing literature over the past several decades supports the safety of LIFUS and its ability to noninvasively modulate neural tissue in animals and humans by positioning the beam over various brain regions to target motor, s

SUBMITTER: Bubrick EJ 

PROVIDER: S-EPMC9684587 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature