Applying post-neoadjuvant pathologic stage as prognostic tool in esophageal squamous cell carcinoma.

ABSTRACT:

Background

It is still uncertain whether the newly released eighth American Joint Committee on Cancer (AJCC) post-neoadjuvant pathologic (yp) tumor-node-metastasis (TNM) stage for esophageal carcinoma can perform well regarding patient stratification. The current study aimed to assess the prognostication ability of the eighth AJCC ypTNM staging system and attempted to explore how to facilitate the staging system for more effective evaluation of prognosis.

Materials and methods

A total of 486 patients treated with neoadjuvant radiotherapy/chemoradiotherapy (nRT/CRT) were enrolled. ypN stage was reclassified by recursive partitioning. Prognostic performance, monotonicity, homogeneity, and discriminatory of yp and modified yp (myp) staging systems were assessed by time-dependen

SUBMITTER: Han W 

PROVIDER: S-EPMC9685303 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature