Coating formulation change leads to inferior performance of long-lasting insecticidal nets in Papua New Guinea.

ABSTRACT:

Background

Long-lasting insecticidal nets (LLINs) play a key role in reducing malaria transmission in endemic countries. In a previous study, the authors demonstrated a substantial decrease in the bioefficacy of LLINs for malaria prevention delivered to Papua New Guinea (PNG) between 2013 and 2019. This coincided with a rise in malaria cases in the country. The present study was aimed at determining the underlying cause of the reduced bioefficacy observed in these LLINs. The main hypothesis was that a change in the coating formulation of the respective LLIN product was responsible, and had led to significantly altered product properties and performance.

Methods

A set of PermaNet^® 2.0 LLIN samples (n = 12) manufactured between 2007 and 2019 was subjected to combust

SUBMITTER: Bubun N 

PROVIDER: S-EPMC9685832 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature