Introducing new plan evaluation indices for prostate dose painting IMRT plans based on apparent diffusion coefficient images.

ABSTRACT:

Background

Dose painting planning would be more complicated due to different levels of prescribed doses and more complex evaluation with conventional plan quality indices considering uniform dose prescription. Therefore, we tried to introduce new indices for evaluating the dose distribution conformity and homogeneity of treatment volumes based on the tumoral cell density and relative volumes of each lesion in prostate IMRT.

Methods

CT and MRI scans of 20 male patients having local prostate cancer were used for IMRT DP planning. Apparent diffusion coefficient (ADC) images were imported to a MATLAB program to identify lesion regions based on ADC values automatically. Regions with ADC values lower than 750 mm²/s and regions with ADC values higher than 750 and less th

SUBMITTER: Moradi S 

PROVIDER: S-EPMC9685857 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature