Association between serum homocysteine and sarcopenia among hospitalized older Chinese adults: a cross-sectional study.

ABSTRACT:

Objective

Hyperhomocysteinemia (HHcy) is considered to increase the risk of sarcopenia (S) and remains controversial. In this study, we aimed to investigate the prevalence of S among older Chinese adults and explore whether homocysteine (Hcy) was independently associated with S.

Methods

This cross-sectional study was performed among older adults hospitalized in the Geriatric Hospital of Nanjing Medical University between June 2017 and December 2021. We measured all participants' serum Hcy levels, hand grip strength, gait speed and appendicular skeletal muscle index(ASMI) using bioelectrical impedance analysis (BIA). S was defined based on the criteria of the Asian Working Group for Sarcopenia 2 (AWGS2), which included muscle mass (ASMI< 7.0 kg/m² for men and ASMI<

SUBMITTER: Lu B 

PROVIDER: S-EPMC9685861 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature