Association between hypomagnesemia and coagulopathy in sepsis: a retrospective observational study.

ABSTRACT:

Background

Hypomagnesemia reportedly has significant associations with poor clinical outcomes such as increased mortality and septic shock in patients with sepsis. Although the mechanism underlying these outcomes mostly remains unclear, some experimental data suggest that magnesium deficiency could potentiate coagulation activation in sepsis. However, in sepsis, the association between serum magnesium levels and coagulopathy, including disseminated intravascular coagulation (DIC), remains unknown. Thus, we aimed to investigate the relationship between serum magnesium levels and coagulation status and the association between hypomagnesemia and DIC in patients with sepsis.

Methods

This retrospective observational study was conducted at the intensive care unit (ICU) of a univer

SUBMITTER: Tonai K 

PROVIDER: S-EPMC9685885 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature