Evaluation of CSF albumin quotient in neuronal surface antibody-associated autoimmune encephalitis.

ABSTRACT:

Background and objectives

Disruption of brain barriers is considered to be involved in the pathogenesis of neuronal surface antibody-associated autoimmune encephalitis (NSAE), but few studies have focused on their relationship. We aimed to explore the association between the integrity of brain barriers and clinical and paraclinical characteristics in patients with NSAE.

Methods

This retrospective study consecutively recruited patients with NSAE. The cerebrospinal fluid (CSF) / serum albumin quotient (Qalb) was used to evaluate the function of brain barriers. The data on demographic information, clinical manifestations, magnetic resonance imaging (MRI), CSF findings and prognosis were collected and analyzed.

Results

Of the 93 patients included, 33 (35.5%) patients were

SUBMITTER: Lai QL 

PROVIDER: S-EPMC9685895 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature