The efficacy and safety of intravesical chondroitin sulphate solution in recurrent urinary tract infections.

ABSTRACT:

Background

Urinary tract infections are among the most common indications for antibiotic therapy. The emergence of resistant uropathogens indicates the need for treatment alternatives. Replenishment of the glycosaminoglycan layer of the bladder, achieved by intravesical instillation of e.g. chondroitin sulphate (CS), is described to be a cornerstone in the therapy of cystitis. To retrospectively evaluate the efficacy of a therapy with 0.2% CS in patients suffering recurrent urinary tract infections (rUTI) in comparison to a treatment with low-dose long-term antibiotics (LDLTAB) and a combination of both.

Methods

A total of 151 patients with recurrent UTI who underwent intravesical therapy at Diaconesse hospital in Leiden, The Netherlands were included. 50 patients had been t

SUBMITTER: Rahnama'i MS 

PROVIDER: S-EPMC9685912 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature