Effect of temperature on Escherichia coli bloodstream infection in a nationwide population-based study of incidence and resistance.

ABSTRACT:

Background

The incidence of Escherichia coli bloodstream infections (BSI) is high and increasing. We aimed to describe the effect of season and temperature on the incidence of E. coli BSI and antibiotic-resistant E. coli BSI and to determine differences by place of BSI onset.

Methods

All E. coli BSI in adult Israeli residents between January 1, 2018 and December 19, 2019 were included. We used the national database of mandatory BSI reports and outdoor temperature data. Monthly incidence and resistance were studied using multivariable negative binomial regressions with season (July-October vs. other) and temperature as covariates.

Results

We included 10,583 events, 9012 (85%) community onset (CO) and 1571 (15%) hospital onset (HO). For CO events, for each average month

SUBMITTER: Feldman SF 

PROVIDER: S-EPMC9685946 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature