Computed tomography-measured body composition and survival in rectal cancer patients: a Swedish cohort study.

ABSTRACT:

Background

The association between body composition and survival in rectal cancer patients is still unclear. Therefore, we aimed to evaluate the impact of computed tomography (CT)-measured body composition on survival in rectal cancer patients, stratifying our analyses by sex, tumour location, tumour stage and radiotherapy.

Methods

This retrospective cohort study included 173 patients with rectal adenocarcinoma. CT colonography scans at the time of diagnosis were used to assess the skeletal muscle index (SMI) and the visceral adipose tissue area (VAT). The patients were divided into a low or high SMI group and a low or high VAT group according to previously defined cutoff values. Endpoints included cancer-specific survival (CSS) and overall survival (OS).

Results

In a

SUBMITTER: Kotti A 

PROVIDER: S-EPMC9686115 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature