Modeling the COVID Pandemic: Do Delays in Surgery Justify Using SBRT to Treat Low-Risk Early Stage NSCLC?

ABSTRACT:

Introduction

It was suggested that stereotactic radiation (SBRT) is an "alternative if no surgical capacity is available" for non-small cell lung cancer (NSCLC) care during the COVID-19 pandemic. The purpose of this study was to compare the oncologic outcomes of delayed surgical resection and early SBRT among operable patients with early stage lung cancer.

Methods

The National Cancer Database was queried for patients with cT1aN0M0 NSCLC who underwent surgery or SBRT (2010-2016) with no comorbidity. Patients with any comorbidities or age >80 were excluded. The outcome of interest was overall survival. Delays in surgical care were modeled using different times from diagnosis to surgery. A 1:1 propensity match was performed and survival was analyzed using multivariable Cox regr

SUBMITTER: Cao L 

PROVIDER: S-EPMC9686123 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature