Triplet Photosensitized para-Hydrogen Induced Polarization.

ABSTRACT: Despite its enormous utility in structural characterization, nuclear magnetic resonance (NMR) spectroscopy is inherently limited by low spin polarization. One method to address the low polarization is para-hydrogen (p-H₂) induced polarization (PHIP) which uses the singlet spin isomer of H₂ to generate disparate nuclear spin populations to amplify the associated NMR signals. PHIP often relies on thermal catalysis or, more infrequently, UV-activated catalytic hydrogenation. Light-activated hydrogenation enables direct and timed control over the hyperpolarization of target substrates, critical for identifying short-lived intermediates. Here, we use an established Ir(III) triplet photosensitizer (PS) to visible light sensitize the triplet ligand-field

SUBMITTER: Brown EE 

PROVIDER: S-EPMC9686209 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature