Overview of Antiviral Drug Therapy for COVID-19: Where Do We Stand?

ABSTRACT: The vaccine weapon has resulted in being essential in fighting the COVID-19 outbreak, but it is not fully preventing infection due to an alarming spreading of several identified variants of concern. In fact, the recent emergence of variants has pointed out how the SARS-CoV-2 pandemic still represents a global health threat. Moreover, oral antivirals also develop resistance, supporting the need to find new targets as therapeutic tools. However, cocktail therapy is useful to reduce drug resistance and maximize vaccination efficacy. Natural products and metal-drug-based treatments have also shown interesting antiviral activity, representing a valid contribution to counter COVID-19 outbreak. This report summarizes the available evidence which supports the use of approved drugs and further focu

SUBMITTER: Esposito R 

PROVIDER: S-EPMC9687182 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature