Dataset Information

Agri-Food By-Products in Cancer: New Targets and Strategies.

ABSTRACT: The globalization and the changes in consumer lifestyles are forcing us to face a deep transformation in food demand and in the organization of the entire food production system. In this new era, the food-loss and food-waste security nexus is relevant in the global debate and avoiding unsustainable waste in agri-food systems as well as the supply chain is a big challenge. "Food waste" is useful for the recovery of its valuable components, thus it can assume the connotation of a "food by-product". Sustainable utilization of agri-food waste by-products provides a great opportunity. Increasing evidence shows that agri-food by-products are a source of different bioactive molecules that lower the inflammatory state and, hence, the aggressiveness of several proliferative diseases. This review aims to summarize the effects of agri-food by-products derivatives, already recognized as promising therapeutics in human diseases, including different cancer types, such as breast, prostate, and colorectal cancer. Here, we examine products modulating or interfering in the signaling mediated by the epidermal growth factor receptor.

SUBMITTER: Sorrentino C

PROVIDER: S-EPMC9688227 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature

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Publications

Agri-Food By-Products in Cancer: New Targets and Strategies.

Sorrentino Carmela C Di Gisi Martina M Gentile Giulia G Licitra Fabrizio F D'Angiolo Rosa R Giovannelli Pia P Migliaccio Antimo A Castoria Gabriella G Di Donato Marzia M

Cancers 20221110 22

The globalization and the changes in consumer lifestyles are forcing us to face a deep transformation in food demand and in the organization of the entire food production system. In this new era, the food-loss and food-waste security nexus is relevant in the global debate and avoiding unsustainable waste in agri-food systems as well as the supply chain is a big challenge. "Food waste" is useful for the recovery of its valuable components, thus it can assume the connotation of a "food by-product" ...[more]

PMID: 36428610

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Project description:The agri-food systems face many global and local challenges, including climate change, environmental degradation, and loss of biodiversity. As the global population continues to rise, the demand for food and other ecosystem services also increases, escalating the pressure on agri-food systems. There is an urgent need to transition agri-food systems' goals from production efficiency to sustainability to address these challenges. Within agri-food systems, niche marketing has gained prominence in achieving sustainability. Using the PRISMA framework, this study performs a systematic literature review up to November 2024 to gather existing evidence on how niche markets can promote sustainable agri-food systems while also identifying challenges and policy options. To this end, two databases were employed: Web of Sciences and Scopus. Findings from the selected literature (58 articles) indicate that developing niche markets to deliver sustainable agriculture is subject to various challenges related to risk exposure, entry barriers, changing consumer preferences, and institutional context. In general, three main ways through which niche markets can support sustainable agri-food systems were identified. Firstly, niche markets provide financial incentives to encourage farmers to adopt environmentally friendly practices by increasing the price premiums and limiting competitors' market access. Secondly, niche markets facilitate partnerships and networks that enable sharing know-how and best practices, reducing the high cost of transitioning to sustainable production systems. Thirdly, niche markets promote radical innovations and technologies that enable increased economic efficiency and environmental performance. In terms of policy implications, public initiatives fostering the expansion of niche markets in agri-food production should increase financial support, access to credit, and legal recognition of certifications for environmentally friendly products. Other measures include fostering knowledge transfer and networking between farmers and consumers.

Dataset Information

Agri-Food By-Products in Cancer: New Targets and Strategies.

Publications

Agri-Food By-Products in Cancer: New Targets and Strategies.

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