Hyperspectral Imaging in Major Hepatectomies: Preliminary Results from the Ex-Machyna Trial.

ABSTRACT: Ischemia-reperfusion injury during major hepatic resections is associated with high rates of post-operative complications and liver failure. Real-time intra-operative detection of liver dysfunction could provide great insight into clinical outcomes. In the present study, we demonstrate the intra-operative application of a novel optical technology, hyperspectral imaging (HSI), to predict short-term post-operative outcomes after major hepatectomy. We considered fifteen consecutive patients undergoing major hepatic resection for malignant liver lesions from January 2020 to June 2021. HSI measures included tissue water index (TWI), organ hemoglobin index (OHI), tissue oxygenation (StO₂%), and near infrared (NIR). Pre-operative, intra-operative, and post-operative serum and clinical

SUBMITTER: Felli E 

PROVIDER: S-EPMC9688371 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature