Non-Invasive and Real-Time Monitoring of the Breast Cancer Metastasis Degree via Metabolomics.

ABSTRACT: Breast cancer (BC) is a serious threat to women's health and metastasis is the major cause of BC-associated mortality. Various techniques are currently used to preoperatively describe the metastatic status of tumors, based on which a comprehensive treatment protocol was determined. However, accurately staging a tumor before surgery remains a challenge, which may lead to the miss of optimal treatment options. More severely, the failure to detect and remove occult micrometastases often causes tumor recurrences. There is an urgent need to develop a more precise and non-invasive strategy for the detection of the tumor metastasis in lymph nodes and distant organs. Based on the facts that tumor metastasis is closely related to the primary tumor microenvironment (TME) evolutions and that metabolo

SUBMITTER: Zhu W 

PROVIDER: S-EPMC9688400 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature