Serial Changes in Body Composition and the Association with Disease Activity during Treatment in Patients with Crohn's Disease.

ABSTRACT: Objectives: To analyze serial changes in body composition and investigate the association between body composition changes and disease activity changes in patients with Crohn’s disease (CD). Methods: Seventy-one patients with CD who had been treated and followed-up at our institution were included. Two to four computed tomography images were acquired at baseline, and the 2−5-year, 5−8-year, and last follow-ups were selected per patient for body composition and disease activity analyses. Visceral fat area (VFA), skeletal muscle index (SMI; skeletal muscle area/height2), and subcutaneous fat area (SFA) were assessed using an artificial-intelligence-driven fully automated method. Disease activity was assessed using a modified computed tomography scoring system and the Simple Endoscopic Score

SUBMITTER: Lee JY 

PROVIDER: S-EPMC9689369 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature