Secular Trends in Systemic Sclerosis Mortality in the United States from 1981 to 2020.

ABSTRACT:

Background

Systemic sclerosis (SSc) has the highest mortality rate among autoimmune disorders. Individuals with SSc frequently die from complications or infections related to SSc. Nonetheless, the sex-age-period interaction of SSc is complex and remains unclear. The study aims to analyze the secular trend of SSc mortality based on data regarding underlying cause of death (UCD) and multiple causes of death (MCD) and clarify the sex-age interaction with time.

Methods

The multiple-cause mortality statistics provided by the National Center for Health Statistics were used to identify all deaths in the United States from 1981 to 2020 in which SSc was indicated anywhere on the death certificates. The age-standardized mortality rate (ASMR) was determined for both sexes, as well as t

SUBMITTER: Li JX 

PROVIDER: S-EPMC9690027 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature