Association between Menopausal Hormone Therapy and Frailty: Cross-Sectional Study Using National Survey Data in Korea.

ABSTRACT: Frailty is a multidimensional clinical syndrome that increases the risk of adverse health outcomes. Previous studies have reported a close link between menopause and frailty. Combined estrogen-progestin therapy (or estrogen-only therapy in women who have undergone a hysterectomy) is currently approved as a menopausal hormone therapy (MHT) to treat menopausal symptoms. Despite increasing evidence of the importance of sex hormones in the development of frailty, very few studies have investigated the association between MHT and frailty. A cross-sectional evaluation was conducted using population-based survey data known as the Korea National Health and Nutrition Examination Survey (KNHANES IV-V, 2008-2012). The KNHANES data provided variables that were used to construct a 51-item frailty index

SUBMITTER: Kim H 

PROVIDER: S-EPMC9690075 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature