Radiosensitization-Related Cuproptosis LncRNA Signature in Non-Small Cell Lung Cancer.

ABSTRACT: A new treatment modality targeting cuproptosis is gradually entering the public horizon. Cuproptosis is a new form of regulated cell death distinct from ferroptosis, apoptosis, autophagy, and necrosis. Previous studies have discovered that the copper level varies considerably in various cancers and that an increase in copper content is directly associated with the proliferation and metastasis of cancer cells. In non-small cell lung cancer (NSCLC) after radiation, the potential utility of cuproptosis-related long noncoding RNAs (lncRNAs) is still unclear. This research aimed to develop a prediction signature based on lncRNAs associated with cuproptosis to predict the prognosis of NSCLC patients following radiation. Methods: Expression data of primary tumors and adjacent solid tissues were d

SUBMITTER: Xu Q 

PROVIDER: S-EPMC9690519 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature