Compound and Conditioned Likelihood Ratio Behavior within a Probabilistic Genotyping Context.

ABSTRACT: In cases where multiple questioned individuals are separately supported as contributors to a mixed DNA profile, guidance documents recommend performing a comparison to see if there is support for their joint contribution. Anecdotal observations suggest the summed log of the individual likelihood ratios (LR), termed the simple LR product, should be roughly equivalent to or less than the log(LR) for the joint likelihood ratio, termed the compound LR. To assist casework analysts in evaluating statistical weights applied to a case at hand, this study assessed how consistently compound LRs conform to an additive behavior when compared to the simple LR product counterparts. Two-, three-, and four-person DNA mixture data, of various mixture proportions and DNA inputs, were interpreted by STRmix

SUBMITTER: Duke K 

PROVIDER: S-EPMC9690711 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature