Bioinformatic Characterization and Molecular Evolution of the <i>Lucina pectinata</i> Hemoglobins.

ABSTRACT: (1) Introduction: Lucina pectinata is a clam found in sulfide-rich mud environments that has three hemoglobins believed to be responsible for the transport of hydrogen sulfide (HbI_Lp) and oxygen (HbII_Lp and HbIII_Lp) to chemoautotrophic endosymbionts. The physiological roles and evolution of these globins in sulfide-rich environments are not well understood. (2) Methods: We performed bioinformatic and phylogenetic analyses with 32 homologous mollusk globin sequences. Phylogenetics suggests a first gene duplication resulting in sulfide binding and oxygen binding genes. A more recent gene duplication gave rise to the two oxygen-binding hemoglobins. Multidimensional scaling analysis of the sequence space shows evolutionary drift of HbII_Lp and

SUBMITTER: Montes-Rodriguez IM 

PROVIDER: S-EPMC9690805 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature