Treatment Outcomes in the Primary Tube Versus Trabeculectomy Study after 5 Years of Follow-up.

ABSTRACT:

Purpose

To report 5-year treatment outcomes in the Primary Tube Versus Trabeculectomy (PTVT) Study.

Design

Multicenter randomized clinical trial.

Participants

A total of 242 eyes of 242 patients with medically uncontrolled glaucoma and no previous incisional ocular surgery, including 125 patients in the tube group and 117 patients in the trabeculectomy group.

Methods

Patients were enrolled at 16 clinical centers and randomly assigned to treatment with a tube shunt (350-mm² Baerveldt glaucoma implant) or trabeculectomy with mitomycin C (MMC) (0.4 mg/ml for 2 minutes).

Main outcome measures

The primary outcome measure was the rate of surgical failure, defined as intraocular pressure (IOP) > 21 mmHg or reduced < 20% from baseline, IOP ≤ 5 mmHg, r

SUBMITTER: Gedde SJ 

PROVIDER: S-EPMC9691551 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature