The roles of newborn anthropometrics in the association between maternal weight gain and childhood cardiovascular risks.

ABSTRACT:

Objective

The aim was to study the association between newborn anthropometrics and childhood cardiovascular risks and whether newborn anthropometrics mediate the effect of maternal gestational weight gain (GWG) on childhood risks.

Methods

Data of 926 mother-child dyads from the Hyperglycemia and Adverse Pregnancy Outcomes study were analyzed. Newborn anthropometrics were treated as predictors and mediators by using a regression model and causal mediation model, respectively.

Results

Newborn sum of skinfolds (SSF) was associated with childhood diastolic blood pressure (DBP) and pulse wave velocity (coefficients [95% CI]: 0.13 [0.06 to 0.20]; 0.08 [0.004 to 0.15]), whereas newborn ponderal index (PI) was inversely associated with childhood systolic blood pressure (SBP),

SUBMITTER: He Y 

PROVIDER: S-EPMC9691555 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature