Altered cerebellar functional connectivity in chronic subcortical stroke patients.

ABSTRACT:

Background

Previous studies demonstrated that cerebellar subregions are involved in different functions. Especially the cerebellar anterior lobe (CAL) and cerebellar posterior lobe (CPL) have been postulated to primarily account for sensorimotor and cognitive function, respectively. However, the functional connectivity (FC) alterations of CAL and CPL, and their relationships with behavior performance in chronic stroke participants are unclear so far.

Materials and methods

The present study collected resting-state fMRI data from thirty-six subcortical chronic stroke participants and thirty-eight well-matched healthy controls (HCs). We performed the FC analysis with bilateral CAL and CPL as seeds for each participant. Then, we detected the FC difference between the two groups

SUBMITTER: Hong W 

PROVIDER: S-EPMC9691772 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature