In Vitro Screening for Anti-Acetylcholinesterase and Antioxidant Activities of Hottonia palustris L. Extracts and Their Unusual Flavonoids.

ABSTRACT: Hottonia palustris L. is from the genus Hottonia (Primulaceae), and the understanding of its phytochemical and pharmacological properties is limited. In this study, the use of chromatographic techniques led to the isolation of a further eleven compounds, including three new flavonoids: 2',5-dihydroxyflavone 2'-O-β-glucopyranoside, 5,6-dihydroxyflavone 6-O-(6"-O-glucopyranosyl)-β-glucopyranoside (hottonioside A), and 4',5,7-trihydroxyflavone 7-O-(2"-O-β-glucuronide)-β-glucopyranoside. Their structures were determined using extensive 1D and 2D NMR data and mass spectrometry (HRMS). The qualitative assessment of the chemical composition of the investigated extracts and fractions was performed using the LC-HRMS techni

SUBMITTER: Strawa JW 

PROVIDER: S-EPMC9692424 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature