Body Weight and Metabolic Rate Changes in Narcolepsy: Current Knowledge and Future Directions.

ABSTRACT: Narcolepsy is a known auto-immune disease that presents mainly in the teenage years with irresistible sleep attacks. Patients with narcolepsy, especially NT1, have been found to have a high prevalence of obesity and other metabolic derangements. This narrative review aimed to address the relationship between narcolepsy and changes in weight and metabolic rate, and discuss potential mechanisms for weight gain and metabolic changes and future research agendas on this topic. This article will provide a balanced, up-to-date critical review of the current literature, and delineate areas for future research, in order to understand the pathophysiological metabolic changes in narcolepsy. Articles using predefined keywords were searched for in PubMed and Google Scholar databases, with predefined in

SUBMITTER: Dhafar HO 

PROVIDER: S-EPMC9693066 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature