Adaptation of Saccharomyces Species to High-Iron Conditions.

ABSTRACT: Iron is an indispensable element that participates as an essential cofactor in multiple biological processes. However, when present in excess, iron can engage in redox reactions that generate reactive oxygen species that damage cells at multiple levels. In this report, we characterized the response of budding yeast species from the Saccharomyces genus to elevated environmental iron concentrations. We have observed that S. cerevisiae strains are more resistant to high-iron concentrations than Saccharomyces non-cerevisiae species. Liquid growth assays showed that species evolutionarily closer to S. cerevisiae, such as S. paradoxus, S. jurei, S. mikatae, and S. arboricola, were more resistant to high-iron levels than the more dist

SUBMITTER: Sorribes-Dauden R 

PROVIDER: S-EPMC9693265 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature