Calculation of an Improved Stiffness Index Using Decomposed Radial Pulse and Digital Volume Pulse Signals.

ABSTRACT: The stiffness index (SI) is used to estimate cardiovascular risk in humans. In this study, we developed a refined SI for determining arterial stiffness based on the decomposed radial pulse and digital volume pulse (DVP) waveforms. In total, 40 mature asymptomatic subjects (20 male and 20 female, 42 to 76 years of age) and 40 subjects with type 2 diabetes mellitus (T2DM) (23 male and 17 female, 35 to 78 years of age) were enrolled in this study. We measured subjects' radial pulse at the wrist and their DVP at the fingertip, and then implemented ensemble empirical mode decomposition (EEMD) to derive the orthogonal intrinsic mode functions (IMFs). An improved SI (SI_new) was calculated by dividing the body height by the mean transit time between the first IMF5 peak and the IMF6 trou

SUBMITTER: Wu HT 

PROVIDER: S-EPMC9694699 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature