Ontology highlight
ABSTRACT:
SUBMITTER: Wu K
PROVIDER: S-EPMC9694800 | biostudies-literature | 2022 Nov
REPOSITORIES: biostudies-literature
Wu Keke K Hu Wenshuo W Zhou Bolun B Li Bingke B Li Xiaowen X Yan Quanhui Q Chen Wenxian W Li Yuwan Y Ding Hongxing H Zhao Mingqiu M Fan Shuangqi S Yi Lin L Chen Jinding J
International journal of molecular sciences 20221116 22
Porcine circovirus type 2 (PCV2) is capable of causing porcine circovirus-associated disease (PCVAD) and is one of the major threats to the global pig industry. The nucleocapsid protein Cap encoded by the PCV2 ORF2 gene is an ideal antigen for the development of PCV2 subunit vaccines, and its N-terminal nuclear localization sequence (NLS) structural domain is essential for the formation of self-assembling VLPs. In the present study, we systematically expressed and characterized full-length PCV2 ...[more]