The Relationship between Neuropsychiatric Symptoms and Cognitive Performance in Older Adults with Normal Cognition.

ABSTRACT: Background and Objectives: To explore whether specific Neuropsychiatric Symptoms (NPS) are related to worse performance in particular cognitive domains. Materials and Methods: A cross-sectional analysis of the baseline evaluations of older (≥60 years), cognitively unimpaired (CU) participants from the National Alzheimer's Coordinating Center (NACC) Uniform Data Set was performed. Data were derived from 43 Alzheimer's Disease Research Centers. Cognitively impaired individuals, participants with psychiatric disorders and/or under treatment with antipsychotic, anxiolytic, sedative, or hypnotic agents were excluded. NPS were assessed using the Neuropsychiatric Inventory Questionnaire. The association of NPS with participants' performance on episodic memory, semantic memory, langu

SUBMITTER: Liampas I 

PROVIDER: S-EPMC9694960 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature