Assisted Extraction with Cyclodextrins as a Way of Improving the Antidiabetic Activity of Actinidia Leaves.

ABSTRACT: Five varieties of Actinidia leaves (Geneva, Jumbo, Ken's Red, Kijivska Hibridna, and Sentyabraskaya) were analyzed. The profiles of active compounds were determined, namely quercetin, rutin, epicatechin, chlorogenic acid, and kaempferol, in the raw material. Suspecting that the raw material might prove important in the treatment of diabetes, the authors assessed the antioxidant activity and the ability to inhibit enzymes responsible for the development of diabetes (α-glucosidase and α-amylase). As a result of the conducted analysis, the Ken's Red variety was indicated as having the highest biological activity (DPPH IC₅₀ = 0.332 ± 0.048; FRAP IC_0.5 = 0.064 ± 0.005; α-glucosidase inhibition IC₅₀ = 0.098 ± 0.007; α-amylase inhibition IC₅₀ = 0

SUBMITTER: Sip S 

PROVIDER: S-EPMC9695090 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature