Bud-Poplar-Extract-Embedded Chitosan Films as Multifunctional Wound Healing Dressing.

ABSTRACT: Wounds represent a major global health challenge. Acute and chronic wounds are sensitive to bacterial infection. The wound environment facilitates the development of microbial biofilms, delays healing, and promotes chronic inflammation processes. The aim of the present work is the development of chitosan films embedded with bud poplar extract (BPE) to be used as wound dressing for avoiding biofilm formation and healing delay. Chitosan is a polymer with antimicrobial and hydrating properties used in wound dressing, while BPE has antibacterial, antioxidative, and anti-inflammatory properties. Chitosan-BPE films showed good antimicrobial and antibiofilm properties against Gram-positive bacteria and the yeast Candida albicans. BPE extract induced an immunomodulatory effect on human macr

SUBMITTER: Russo C 

PROVIDER: S-EPMC9695786 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature