Mushroom Polysaccharides as Potential Candidates for Alleviating Neurodegenerative Diseases.

ABSTRACT: Neurodegenerative diseases (NDs) are a widespread and serious global public health burden, particularly among the older population. At present, effective therapies do not exist, despite the increasing understanding of the different mechanisms of NDs. In recent years, some drugs, such as galantamine, entacapone, riluzole, and edaravone, have been proposed for the treatment of different NDs; however, they mainly concentrate on symptom management and confer undesirable side effects and adverse reactions. Therefore, there is an urgent need to find novel drugs with fewer disadvantages and higher efficacy for the treatment of NDs. Mushroom polysaccharides are macromolecular complexes with multi-targeting bioactivities, low toxicity, and high safety. Some have been demonstrated to exhibit neuropr

SUBMITTER: Jiang X 

PROVIDER: S-EPMC9696021 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature