Identification of Antidiabetic Compounds from the Aqueous Extract of Sclerocarya birrea Leaves.

ABSTRACT: Diabetes, a prevalent metabolic condition with a wide range of complications, is fast becoming a global health crisis. Herbal medicine and enhanced extracts are some of the therapeutic options used in the management of diabetes mellitus. The plant-derived molecules and their suitable structure modification have given many leads or drugs to the world such as metformin used as an antidiabetic drug. The stem extract of Sclerocarya birrea has been reported as a potent antidiabetic (glucose uptake) agent. However, the bioactive compounds have not been reported from S. birrea for treatment of diabetes. In this study, the spray-dried aqueous leaf extracts of S. birrea were investigated as an antidiabetic agent using a 2-deoxy-glucose (2DG) technique showing good stimulatory e

SUBMITTER: Maharaj V 

PROVIDER: S-EPMC9696724 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature