Therapeutic Potential of Targeting Mitochondria for Alzheimer's Disease Treatment.

ABSTRACT: Alzheimer's disease (AD), a chronic and progressive neurodegenerative disease, is characterized by memory and cognitive impairment and by the accumulation in the brain of abnormal proteins, more precisely beta-amyloid (β-amyloid or Aβ) and Tau proteins. Studies aimed at researching pharmacological treatments against AD have focused precisely on molecules capable, in one way or another, of preventing/eliminating the accumulations of the aforementioned proteins. Unfortunately, more than 100 years after the discovery of the disease, there is still no effective therapy in modifying the biology behind AD and nipping the disease in the bud. This state of affairs has made neuroscientists suspicious, so much so that for several years the idea has gained ground that AD is not a direct neuropatholog

SUBMITTER: Atlante A 

PROVIDER: S-EPMC9697019 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature