Plant as an Alternative Source of Antifungals against Aspergillus Infections: A Review.

ABSTRACT: Aspergillus species consists of a group of opportunistic fungi that is virulent when the immunity of the host is compromised. Among the various species, Aspergillus fumigatus is the most prevalent species. However, the prevalence of fungal infections caused by non-fumigatus Aspergillus has been increasing. Polyenes, echinocandins and azoles are the three main classes of antifungal agents being used for the treatment of aspergillosis. Nevertheless, the incidence of resistance towards these three classes has been rising over the years among several Aspergillus spp. The side effects associated with these conventional antifungal agents have also limited their usage. This urges the need for the discovery of a safe and effective antifungal agent, which presents a majo

SUBMITTER: Tan LF 

PROVIDER: S-EPMC9697101 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature