Re-Entry Evaluation of Chinese Blood Donors with Unconfirmed Hepatitis B Screening Results.

ABSTRACT: The hepatitis B virus (HBV) remains a high priority for Chinese blood banks due to the high prevalence of infection. HBV blood safety has been significantly improved by the implementation of highly sensitive and specific serological and molecular HBV screening assays. The multiplication of viral markers tested and the ever-increasing analytical sensitivity of the tests can make the interpretation of the results difficult. False-positive or indeterminate results may lead to permanent donor deferrals and conflicts between donors and blood banks. To avoid blood shortages, blood services aim to limit unnecessary donor losses by developing procedures for the re-entry of donors temporarily deferred due to an unconfirmed HBV reactivity. The development of such procedures based on donor follow-up

SUBMITTER: Deng X 

PROVIDER: S-EPMC9698129 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature