Association of Short-Term Exposure to PM_2.5 with Blood Lipids and the Modification Effects of Insulin Resistance: A Panel Study in Wuhan.

ABSTRACT: Results of previous studies about the acute effects of fine particulate matter (PM_2.5) on blood lipids were inconsistent. This study aimed to quantify the short-term effects of PM_2.5 on blood lipids and estimate the modifying role of insulin resistance, reflected by the homeostasis model assessment of insulin resistance (HOMA-IR). From September 2019 to January 2020, the study recruited 70 healthy adults from Wuhan University for a total of eight repeated data collections. At each visit, three consecutive days were monitored for personal exposure to PM_2.5, and then a physical examination was carried out on the fourth day. The linear mixed-effect models were operated to investigate the impact of PM_2.5 over diverse exposure windows on blood lipids.

SUBMITTER: Sun J 

PROVIDER: S-EPMC9698404 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature