Light Microscopy and Proteomic Patterns of Ovulation in Cervical Mucus.

ABSTRACT: There is an increasing number of couples interested in identifying the fertile window for the purpose of conceiving. From what has been published so far, it can be concluded that there are no reliable methods to predict ovulation, and, therefore, to predict the fertile window. Proteins of the cervical mucus (CM) could behave as biomarkers to allow the early and precise identification of ovulation. CM samples were collected from the lumen of the cervical canal from women of reproductive age, on three different days of the same menstrual cycle. Samples were first analyzed and classified by light microscopy. High-resolution mass spectrometry and bioinformatic analysis were performed afterwards to determine the in vivo changes of CM protein composition. CM underwent cyclical changes in its bio

SUBMITTER: Fernandez-Hermida Y 

PROVIDER: S-EPMC9698449 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature