Sex modulates the outcome of subthalamic nucleus deep brain stimulation in patients with Parkinson's disease.

ABSTRACT: There are many documented sex differences in the clinical course, symptom expression profile, and treatment response of Parkinson's disease, creating additional challenges for patient management. Although subthalamic nucleus deep brain stimulation is an established therapy for Parkinson's disease, the effects of sex on treatment outcome are still unclear. The aim of this retrospective observational study, was to examine sex differences in motor symptoms, non-motor symptoms, and quality of life after subthalamic nucleus deep brain stimulation. Outcome measures were evaluated at 1 and 12 months post-operation in 90 patients with Parkinson's disease undergoing subthalamic nucleus deep brain stimulation aged 63.00 ± 8.01 years (55 men and 35 women). Outcomes of clinical evaluations were compar

SUBMITTER: Yuan TS 

PROVIDER: S-EPMC9700096 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature