Dataset Information
Binucleated embryos at the two-cell stage show higher blastocyst formation rates and higher pregnancy and live birth rates compared to non-multinucleated embryos.
Ontology highlight
ABSTRACT:
SUBMITTER: Talbot AL
PROVIDER: S-EPMC9700381 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Publications
Binucleated embryos at the two-cell stage show higher blastocyst formation rates and higher pregnancy and live birth rates compared to non-multinucleated embryos.
Human reproduction open 20221124 4
<h4>Study question</h4>How does nucleus status at the two-cell stage predict blastocysts formation and clinical outcome after single blastocyst transfer?<h4>Summary answer</h4>Binucleated embryos at the two-cell stage (2BI) show higher rates of good quality blastocyst formation, pregnancy and live birth compared to those with one nucleus in each blastomere (2MONO), whereas true multinucleated embryos at the two-cell stage (2MULTI) show lower rates of good quality blastocyst formation and pregnan ...[more]