Multi-level personalization of neuromusculoskeletal models to estimate physiologically plausible knee joint contact forces in children.

ABSTRACT: Neuromusculoskeletal models are a powerful tool to investigate the internal biomechanics of an individual. However, commonly used neuromusculoskeletal models are generated via linear scaling of generic templates derived from elderly adult anatomies and poorly represent a child, let alone children with a neuromuscular disorder whose musculoskeletal structures and muscle activation patterns are profoundly altered. Model personalization can capture abnormalities and appropriately describe the underlying (altered) biomechanics of an individual. In this work, we explored the effect of six different levels of neuromusculoskeletal model personalization on estimates of muscle forces and knee joint contact forces to tease out the importance of model personalization for normal and abnormal musculosk

SUBMITTER: Davico G 

PROVIDER: S-EPMC9700656 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature