Serum LDL-C/HDL-C ratio and the risk of carotid plaques: a longitudinal study.

ABSTRACT:

Background

Dyslipidemia contributes to an increased risk of carotid atherosclerosis. However, the association between the ratio of low-density lipoprotein cholesterol (LDL-C) to high-density lipoprotein cholesterol (HDL-C) and carotid plaque formation has not been well documented. This study aims to assess the role of LDL-C/HDL-C in the risk of carotid plaque formation in a Chinese population.

Methods

We followed 2,191 participants who attended the annual routine health examination. Cox proportional hazards regression, restricted cubic spline (RCS), and subgroup analysis were applied to evaluate the association between the LDL-C/HDL-C ratio and carotid plaques. The hazard ratio (HR) and 95% confidence interval (CI) were used to estimate the strength of the association.

Re

SUBMITTER: Wu Z 

PROVIDER: S-EPMC9700971 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature