Iodine map histogram metrics in early-stage breast cancer: prediction of axillary lymph node metastasis status.

ABSTRACT:

Background

Variations in axillary lymph node (ALN) metastatic potential between different breast cancers lead to microscopical alterations in tumor perfusion heterogeneity. This study investigated the usefulness of histogram metrics from iodine maps in the preoperative diagnosis of metastatic ALNs in patients with early-stage breast cancer.

Methods

Between October 2020 and November 2021 enhanced spectral computed tomography (CT) was performed in female patients with breast cancer. Quantitative spectral CT parameters and histogram parameters (mean, median, maximum, minimum, 10th percentiles, 90th percentiles, kurtosis, skewness, energy, range, and variance) from iodine maps were compared between patients with metastatic and nonmetastatic ALNs. Continuous variables were compar

SUBMITTER: Zeng F 

PROVIDER: S-EPMC9703105 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature