Multimorbidity and long-term disability and physical functioning decline in middle-aged and older Americans: an observational study.

ABSTRACT: Multimorbidity is highly prevalent and associated with several adverse health outcomes, including functional limitations. While maintaining physical functioning is relevant for all adults, identifying those with multimorbidity at risk for faster rates of physical functioning decline may help to target interventions to delay the onset and progression of disability. We quantified the association of multimorbidity with rates of long-term disability and objective physical functioning decline. In the Health and Retirement Study, we computed the Multimorbidity-Weighted Index (MWI) by assigning previously validated weights (based on physical functioning) to each chronic condition. We used an adjusted negative binomial regression to assess the association of MWI with disability (measured by basic

SUBMITTER: Aubert CE 

PROVIDER: S-EPMC9703785 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature