Tyroviruses are a new group of temperate phages that infect Bacillus species in soil environments worldwide.

ABSTRACT:

Background

Bacteriophages are widely considered to be highly abundant and genetically diverse, with their role in the evolution and virulence of many pathogens becoming increasingly clear. Less attention has been paid on phages preying on Bacillus, despite the potential for some of its members, such as Bacillus anthracis, to cause serious human disease.

Results

We have isolated five phages infecting the causative agent of anthrax, Bacillus anthracis. Using modern phylogenetic approaches we place these five new Bacillus phages, as well as 21 similar phage genomes retrieved from publicly available databases and metagenomic datasets into the Tyrovirus group, a newly proposed group named so due to the conservation of three distinct tyrosine recombinases. Genomic analysis of thes

SUBMITTER: Batinovic S 

PROVIDER: S-EPMC9703825 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature