Increased risk of incident gout in young men with metabolic syndrome: A nationwide population-based cohort study of 3.5 million men.

ABSTRACT:

Background

To date, few studies have focused on risk factors for gout in young people, and large-scale studies on the relationship between metabolic syndrome (MetS) and gout are lacking. We aimed to investigate the association between gout and MetS in a large nationwide population-based cohort of young men who participated in national health examination.

Materials and methods

Cohort included men aged 20-39 years who participated in a health check-up in 2009-2012. A total of 3,569,104 subjects was included in the study, excluding those who had a previous diagnosis of gout or had renal impairment. The outcome was the occurrence of gout, which was defined using the diagnosis code of gout in the claims database. Cox proportional hazard model was used to evaluate the association

SUBMITTER: Eun Y 

PROVIDER: S-EPMC9704360 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature