Dataset Information

International recommendations for plasma Epstein-Barr virus DNA measurement in nasopharyngeal carcinoma in resource-constrained settings: lessons from the COVID-19 pandemic.

ABSTRACT: The effects of the COVID-19 pandemic continue to constrain health-care staff and resources worldwide, despite the availability of effective vaccines. Aerosol-generating procedures such as endoscopy, a common investigation tool for nasopharyngeal carcinoma, are recognised as a likely cause of SARS-CoV-2 spread in hospitals. Plasma Epstein-Barr virus (EBV) DNA is considered the most accurate biomarker for the routine management of nasopharyngeal carcinoma. A consensus statement on whether plasma EBV DNA can minimise the need for or replace aerosol-generating procedures, imaging methods, and face-to-face consultations in managing nasopharyngeal carcinoma is urgently needed amid the current pandemic and potentially for future highly contagious airborne diseases or natural disasters. We completed a modified Delphi consensus process of three rounds with 33 international experts in otorhinolaryngology or head and neck surgery, radiation oncology, medical oncology, and clinical oncology with vast experience in managing nasopharyngeal carcinoma, representing 51 international professional societies and national clinical trial groups. These consensus recommendations aim to enhance consistency in clinical practice, reduce ambiguity in delivering care, and offer advice for clinicians worldwide who work in endemic and non-endemic regions of nasopharyngeal carcinoma, in the context of COVID-19 and other airborne pandemics, and in future unexpected settings of severe resource constraints and insufficiency of personal protective equipment.

SUBMITTER: Lee VH

PROVIDER: S-EPMC9704820 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature

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International recommendations for plasma Epstein-Barr virus DNA measurement in nasopharyngeal carcinoma in resource-constrained settings: lessons from the COVID-19 pandemic.

Lee Victor Ho-Fun VH Adham Marlinda M Ben Kridis Wala W Bossi Paolo P Chen Ming-Yuan MY Chitapanarux Imjai I Gregoire Vincent V Hao Sheng Po SP Ho Cheryl C Ho Gwo Fuang GF Kannarunimit Danita D Kwong Dora Lai-Wan DL Lam Ka-On KO Lam Wai Kei Jacky WKJ Le Quynh-Thu QT Lee Anne Wing-Mui AW Lee Nancy Y NY Leung To-Wai TW Licitra Lisa L Lim Darren Wan-Teck DW Lin Jin-Ching JC Loh Kwok Seng KS Lou Pei-Jen PJ Machiels Jean-Pascal JP Mai Hai-Qiang HQ Mesía Ricard R Ng Wai-Tong WT Ngan Roger Kai-Cheong RK Tay Joshua K JK Tsang Raymond King-Yin RK Tong Chi-Chung CC Wang Hung-Ming HM Wee Joseph T JT

The Lancet. Oncology 20221201 12

The effects of the COVID-19 pandemic continue to constrain health-care staff and resources worldwide, despite the availability of effective vaccines. Aerosol-generating procedures such as endoscopy, a common investigation tool for nasopharyngeal carcinoma, are recognised as a likely cause of SARS-CoV-2 spread in hospitals. Plasma Epstein-Barr virus (EBV) DNA is considered the most accurate biomarker for the routine management of nasopharyngeal carcinoma. A consensus statement on whether plasma E ...[more]

PMID: 36455583

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Dataset Information

International recommendations for plasma Epstein-Barr virus DNA measurement in nasopharyngeal carcinoma in resource-constrained settings: lessons from the COVID-19 pandemic.

Publications

International recommendations for plasma Epstein-Barr virus DNA measurement in nasopharyngeal carcinoma in resource-constrained settings: lessons from the COVID-19 pandemic.

Similar Datasets

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