Effect of online aerobic exercise training in patients with bipolar depression: Protocol of a randomized clinical trial.

ABSTRACT:

Introduction

Bipolar disorder (BD) is a common and debilitating mental illness that affects about 400 million people worldwide, decreasing their functionality and quality of life. Medication and psychotherapy are recommended for treatment of BD, while some evidence indicates that exercise could improve the clinical outcome of BD. This study aims to investigate whether exercise intervention could reduce the mood symptoms and inflammation level of BD.

Methods

This is a longitudinal, interventional, randomized, and single-blind trial. We plan to recruit 94 patients diagnosed with BD in depression episode. Patients will be randomly assigned to treatment as usual + aerobic exercise group (intervention group) and treatment as usual (TAU) only group, at a ratio of 1:1. The interven

SUBMITTER: Wang X 

PROVIDER: S-EPMC9705266 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature